For me it's the Sony MDR-7506 all the way. There's a reason you see them in so many studios and media production facilities. Heck, I even sleep with them on so comfort is not a concern. They stay on when I'm playing drums, and cost under a hundred bucks. When mixing in the studio they're more of a microscope, which is why so many sound engineers rely on them. They're flat, and not there to make your mix sound pretty, but rather give you the truth. And being closed-air there's no bleed-through. You really feel you're in an isolation booth. The design has been around for a great many years, and I'm glad they haven't altered it much.